This study is created by ehealthme based on reports of 93 people who take theophylline and augmentin from the food and drug administration fda, and is updated regularly. Since up to 90% of a theophylline dose is biotransformed, drugs influencing microsomal enzyme systems in the liver may affect the elimination of theophylline. Drug interactions are reported among people who take theophylline and augmentin together. Pdf use of dietary supplements in presurgical patients. Major dietdrug interactions affecting the kinetic characteristics and. Theophylline drug interactions can alter the level of theophylline in your blood or make some drugs less effective, among other things. Find information on cephalexin keflex, panixine in daviss drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Beta agonists must be taken exactly as prescribed because overdosage may be. Many drugs have been found to increase or decrease the clearance of theophylline, probably by interaction with one or more of the variants of the cytochrome p450 drugmetabolising system. We look into the drug interactions by gender and age. Many drugs have been found to increase or decrease the clearance of theophylline, probably by interaction with one or more of the variants of the cytochrome p450 drug metabolising system. Find information on theophylline elixophyllin, theo24 in daviss drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more.
Theophyllines first clinical use came in 1902 as a diuretic. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Evolution of drug metabolism as a science richard tecwyn williams great britain 1942, worked on the metabolism on tnt with regard to toxicity in munitions workers. Theophylline uniphyl and theo24 side effects, dosage. These medications may interact and cause very harmful effects. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is.
Our pdf merger allows you to quickly combine multiple pdf files into one single pdf document, in just a few clicks. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. We would like to show you a description here but the site wont allow us. Frequent cannabis use has been associated with increased inr. Drug interactions may change how your medications work or increase your risk for serious side effects. Theophylline comes as an extendedrelease longacting tablet, extendedrelease capsule, and a solution liquid to take by mouth. However, it is clear that this compound has many of the features usually associated. It took an additional 20 years until it was first reported as an asthma treatment. Table 1 311 and table 2 311 list commonly prescribed cyp1a2 substrates that could be affected by tobacco smoke. Somophyllin tablet generic, side effects, interchangeable. This study is created by ehealthme based on reports of 33 people who take theophylline and caffeine from food and drug administration fda, and is updated regularly. Do not take theophylline if you are addict of tobacco, cannabis and alcohol.
Alcohol, quinidine, and warfarin may potentially cause drug interactions with phenytoin. Beta agonists must be taken exactly as prescribed because overdosage may be life threatening. There are 7 disease interactions with theophylline which include. Pdf interaction between theophylline and tacrolimus in a. Drug interactions theophylline interacts with a wide variety of drugs. The plasma theophylline concentration is decreased in smokers, and by alcohol consumption. The drug is metabolised in the liver by cytochrome p450 isoenzymes, principally cyp1a2, to demethylated and hydroxylated products. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The most common types of seizures are generalized and partial seizures with secondary generalization,151,152 but status epilepticus can occur in approximately 30% of patients.
The plasmatheophylline concentration is increased in heart failure, hepatic impairment, and in viral infections. See what the interactions are and for which people. View interaction reports for theophylline and the medicines listed below. Theophylline is the generic name for the prescription drugs uniphyl in canada and theo24. Blocks adenosine receptors, often necessitating a higher dose of adenosine to achieve the desired effect. This page on the emedtv web site explains what other drugs may cause phenytoin interactions and describes the possible risks of combining them with phenytoin. Pdfsam basic is free and open source and works on windows, mac and linux. Learn about theophylline from patients first hand experiences and trusted online health resources, including dosage, side effects and interactions. Pharmacokinetic interactions between theophylline and other. Theophylline and augmentin drug interactions ehealthme. This medication belongs to a class of drugs known as xanthines.
Somophyllin interactions somophyllin interacts with a wide variety of drugs. Because of its enormous popularity, the consumption of caffeine is generally thought to be safe and long term caffeine intake may be disregarded as a medical problem. Some of the more famous drugdrug interactions to know for the ptce or excpt exams. Theophylline elixophyllin, theo24 daviss drug guide. Many drugs interact with theophylline by inhibiting or potentiating its metabolism by cyp1a2 see. Theophylline toxicity, mainly iatrogenic, can cause seizures in patients without known underlying epilepsy. Theophylline interactions learning article pharmaceutical. Theophylline drug interactions among the drugs that can potentially interact with theophylline are alcohol, cimetidine, and certain antibiotics. Theophylline s first clinical use came in 1902 as a diuretic.
Theophylline oral interactions with other medication. Whatever the mechanism, the interaction may be sufficient to necessitate adjustment of the theophylline dosage, preferably. Differences in the halflife of theophylline are important because the toxic dose is close to the therapeutic dose. The plasma theophylline concentration is increased in heart failure, hepatic impairment, and in viral infections. Theophylline is an oral medication used to treat asthma and other lung diseases. Deze gratis online tool maakt het mogelijk om meerdere pdf bestanden of afbeeldingen te combineren in een pdf document. Theophylline elixophyllin, theo24 is a bronchodilator prescribed for the treatment of asthma and other airway conditions.
Maakt het mogelijk om pdfbestanden samen te voegen met een simpele drag anddrop interface. These substances may show some reactions with theophylline. Theophylline interacts with a wide variety of drugs. The drug was prescribed in a syrup up to the 1970s as theostat 20 and theostat 80, and by the early 1980s in a tablet form called quibron. Theophylline, anhydrous oral tablet, extended release 24 hour. The combiner, which is available in most engines and output modules, has no support for merging jobs. Patients need to monitor inr closely, at least twice a week, as the cannabis will increase the levels this means that the patient will have to decrease the warfarin dosages.
Consequently, neither drug is expected to interact with theophylline. If a second inhaled drug is ordered, instruct the patient wait 2 to 5 minutes between the medications or as prescribed. By continuing to browse this site you are agreeing to our use of cookies. Individual patients may experience larger changes in serum theophylline concentrations than the value listed. Many drugs interact with theophylline by inhibiting or potentiating its metabolism by cyp1a2 see commonlyused drugs that interact with theophylline. Theophylline and caffeine drug interactions a study of fda. Whatever the mechanism, the interaction may be sufficient to necessitate adjustment of the theophylline dosage. If a second puff of the same drug is ordered, instruct the patient to wait 1 to 2 minutes between puffs. Thc and cbd increase warfarin levels yamaori et al 2012. Sep 30, 2012 caffeine from dietary sources mainly coffee, tea and soft drinks is the most frequently and widely consumed cns stimulant in the world today. The aim of stockleys drug interactions is to inform busy doctors, pharma. All interactions with theophylline slophyllin, theodur coadministered drug dose of drug dose of theophylline. The plasmatheophylline concentration is decreased in smokers, and by alcohol consumption. However, there might be a risk of qtinterval prolongation with the concurrent use of theophylline and citalopram, because citalopram has been seen to cause a dosedependent increase in the qtcf interval.
Advair diskus fluticasone salmeterol aminophylline. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Theophylline is a widely used bronchodilator and a very potent central nervous system cns stimulant. Drug interactions are reported among people who take theophylline and caffeine together. Theophylline, anhydrous oral tablet, extended release 24 hour drug summary. Its used to treat airflow obstruction symptoms such as wheezing, shortness of breath, and chest. Drug interactions with phenytoin nervous system home page. Theophylline interactions bnf content published by nice. Calculate initial dosage using the following equation. The aim of this study was to compare the bronchodilating effect, tolerability and acceptability of a single 100g dose of salbutamol inhaled via easyhaler. However, it is clear that this compound has many of the features usually. Caffeine from dietary sources mainly coffee, tea and soft drinks is the most frequently and widely consumed cns stimulant in the world today. Theophylline is used to treat lung diseases such as asthma and copd bronchitis, emphysema. This document does not contain all possible drug interactions.
There are no specific guidelines for how to assess, monitor, or manage pharmacokinetic drug interactions with tobacco smoke. Subscribe to medhelp s free newsletter for community support, experience, and guidance. To reduce the risk of developing potentially dangerous drug interactions with theophylline, you should talk with your healthcare provider or pharmacist about any theophylline interactions that may apply to you. Pharmacokinetic drug interactions with theophylline. If you are taking these drugs together, your healthcare provider should monitor the level of theophylline in your blood and adjust your theophylline dosage as necessary. It must be used regularly to prevent wheezing and shortness of breath. Clinically significant pharmacokinetic interactions between. Theophylline, administered for up to 3 weeks, has been shown to disturb psgrecorded sleep in healthy subjects, 278,279 patients with asthma, 280 children with cystic fibrosis, 281 and patients with sleep apnea 282 or chronic obstructive pulmonary disease. Differences in the halflife of theophylline are important because. Dec, 2012 since up to 90% of a theophylline dose is biotransformed, drugs influencing microsomal enzyme systems in the liver may affect the elimination of theophylline. Aquaphyllin, asmalix, elixophyllin theophylline uses, side.
The clinician should not assume that a drug does not interact with theophylline if it is not listed here. Quickly merge multiple pdf files or part of them into a single one. Theophylline complete drug information, side effects and. It works in the airways by relaxing muscles, opening breathing passages. Theophylline drug, uses, dose, tablets, side effects. Taking theophylline with propranolol can greatly increase the level of theophylline in your blood, which can cause dangerous side effects. Learn who its for, how it works, its side effects, warnings, and more.
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